AstraZeneca and Sun Pharma Join Forces in India

Nov 21, 2025 | Pharma

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AstraZeneca and Sun Pharma Join Forces to Expand Access to Hyperkalaemia Treatment in India

In a major development for renal and cardiac care in India, AstraZeneca Pharma India and Sun Pharmaceutical Industries have announced a strategic co-marketing partnership to distribute Sodium Zirconium Cyclosilicate (SZC), an advanced therapy for hyperkalaemia, across the country. A broader overview of hyperkalaemia and its clinical impact can be found through resources such as the National Kidney Foundation (https://www.kidney.org/atoz/content/hyperkalemia).

Two Brands. One Mission.

Under the agreement, AstraZeneca will market the drug under its global brand Lokelma, while Sun Pharma will distribute the same molecule under a new local brand called Gimliand. AstraZeneca will continue to hold the intellectual property, marketing authorization, and import license for the therapy. For more information on SZC’s mechanism of action, readers can reference the European Medicines Agency product summary (https://www.ema.europa.eu/en/medicines/human/EPAR/lokelma).

Why This Matters

Hyperkalaemia — elevated potassium levels in the bloodstream — is a potentially dangerous condition commonly associated with chronic kidney disease and heart failure. Up to half of CKD patients and over 40% of heart failure patients may experience hyperkalaemia at some point. A clinical overview of the condition is available via UpToDate (https://www.uptodate.com/contents/hyperkalemia-in-adults).

Sodium Zirconium Cyclosilicate is considered a rapid and well-tolerated therapeutic option. Healthcare providers seeking detailed prescribing information may consult the FDA-approved label for SZC (https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/209073s000lbl.pdf).

A Strategic Alliance with Patient Outcomes at Heart

AstraZeneca’s leadership highlights the partnership as part of its mission to deliver life-changing medicines. Sun Pharma, with one of the largest field forces in the pharmaceutical industry, sees the collaboration as an expansion of its chronic and renal care focus. Insights into the broader partnership strategy between major pharma companies can be explored through Pharmaceutical Technology’s analysis of co-marketing trends (https://www.pharmaceutical-technology.com/features/pharma-partnerships-analysis).

The Stakes Are High and So Is the Potential Impact

Hyperkalaemia is a serious and sometimes life-threatening condition. In India, mortality rates in high-risk patients can be significant when hyperkalaemia goes untreated. By combining AstraZeneca’s innovation with Sun Pharma’s distribution network, the partnership aims to improve nationwide access to SZC and support safer management of chronic kidney disease.

Market Reaction

Following the announcement, AstraZeneca Pharma India’s shares saw a positive surge, reflecting confident market sentiment toward the deal and its growth potential in the renal-care space.

Looking Ahead

This agreement marks the second brand partnership between AstraZeneca and Sun Pharma in India, signaling the growing strength of their collaboration. Both companies intend to expand patient access, improve clinical education, and increase awareness of hyperkalaemia, a condition that remains under-recognised despite its clinical significance.

    References:
    1. National Kidney Foundation – Hyperkalaemia Overview https://www.kidney.org/atoz/content/hyperkalemia
    2. European Medicines Agency – Lokelma (Sodium Zirconium Cyclosilicate) https://www.ema.europa.eu/en/medicines/human/EPAR/lokelma
    3. UpToDate – Hyperkalemia in Adults (Clinical Overview) https://www.uptodate.com/contents/hyperkalemia-in-adults
    4. FDA Label – Sodium Zirconium Cyclosilicate (SZC) https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/209073s000lbl.pdf
    5. Pharmaceutical Technology – Pharma Partnership Trends Analysis https://www.pharmaceutical-technology.com/features/pharma-partnerships-analysis

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